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Atypical behaviour and connectivity in SHANK3-mutant macaques
Nature, Published online: 12 June 2019; doi:10.1038/s41586-019-1278-0
The CRISPR–Cas9-mediated generation of germline-transmissible mutations of SHANK3 in cynomolgus macaques (Macaca fascicularis) forms the basis of a non-human-primate model of autism spectrum disorder and Phelan–McDermid syndrome.