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Developmental ROS individualizes organismal stress resistance and lifespan

Nature, Published online: 04 December 2019; doi:10.1038/s41586-019-1814-y

A subpopulation of Caenorhabditis elegans, in which there is a naturally occurring transient increase in reactive oxygen species during early development, exhibits increased stress resistance, improved redox homeostasis and prolonged lifespan, which are linked to a global decrease in level of the histone mark H3K4me3.

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