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CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle
Nature, Published online: 13 November 2019; doi:10.1038/s41586-019-1744-8
A phospho-switch is identified in the shelterin subunit TRF2 that regulates transient recruitment of the RTEL1 helicase to, and release from, telomeres, and provides a narrow window during which RTEL1 can unwind t-loops to facilitate telomere replication.