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Pol II phosphorylation regulates a switch between transcriptional and splicing condensates
Nature, Published online: 07 August 2019; doi:10.1038/s41586-019-1464-0
RNA polymerase II with a hypophosphorylated C-terminal domain preferentially incorporates into mediator condensates, and with a hyperphosphorylated C-terminal domain into splicing-factor condensates, revealing phosphorylation as a regulatory mechanism in condensate preference.