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Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism
Nature, Published online: 31 July 2019; doi:10.1038/s41586-019-1442-6
The harvest of large quantities of lysine by yeast and other microbes triggers a reprogramming of redox metabolism, in which NADPH is channelled into glutathione metabolism to reduce levels of reactive oxygen species and increase tolerance to oxidative stress.