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Opposing T cell responses in experimental autoimmune encephalomyelitis
Nature, Published online: 07 August 2019; doi:10.1038/s41586-019-1467-x
Activated clonally expanded CD4+ T cells display specificity to the myelin peptide MOG, whereas clonally expanded CD8+ T cells depend on T cell receptor recognition of unrelated surrogate peptides and have a regulatory function.
