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Human heart cells are altered by spaceflight, but return to (mostly) normal on Earth

Heart muscle cells derived from stem cells show remarkable adaptability to their environment during and after spaceflight, according to a new study. The researchers examined cell-level cardiac function and gene expression in human heart cells cultured aboard the International Space Station for 5.5 weeks. Exposure to microgravity altered the expression of thousands of genes, but largely normal patterns of gene expression reappeared within 10 days after returning to Earth.

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